Breaking down nerve-cell scaffold relieves chronic pain in mice

Nature2026年10月9日正文已收录本站
  • RESEARCH HIGHLIGHT

Results could help researchers to develop painkillers that are safer and more effective than existing treatments.

Illustration of a nerve cell with a bright glowing orange centre and branching, thread-like extensions stretching outwards

Neurons (artist’s illustration) that remain in a hyperactive state can give rise to chronic pain. Credit: Ruslanas Baranauskas/Science Photo Library

Unplugging the cellular machinery that amplifies pain signals provides relief for mice with chronic nerve injuries1.

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doi: https://doi.org/10.1038/d41586-026-03159-z

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