Location, location, location: how to edit genes only in the cells you want

Nature2026年10月2日正文已收录本站
  • RESEARCH HIGHLIGHT

Gene-editing CRISPR enzymes controlled by light and sound target tissues of interest.

Artist’s illustration showing several adeno-associated virus particles as multicolored, spherical structures against a black background

Scientists used viral particles (artist’s impression) to carry light-controlled gene editors into cells. Credit: Kateryna Kon/SPL

Light and sound can be used to turn on CRISPR gene-editing tools and make targeted alterations to the genome in specific tissues in mice1.

Access options

Access through your institution

Access Nature and 54 other Nature Portfolio journals

Get Nature+, our best-value online-access subscription

27,99 € / 30 days

cancel any time

Subscription info for Chinese customers

We have a dedicated website for our Chinese customers. Please go to naturechina.com to subscribe to this journal.

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

doi: https://doi.org/10.1038/d41586-026-03037-8

References

Subjects