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Sugar amplifies antibiotic disruption of gut microbes

Nature作者：Mengxi Du2026年9月30日正文已收录本站
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People who underwent stem-cell transplantation and ate sugar-rich food had disrupted communities of gut microorganisms during antibiotic treatment.

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  1. Mengxi Du

    1. Mengxi Du is in the Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA, and in the Department of Epidemiology and the Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

  2. Andrew T. Chan

    1. Andrew T. Chan is in the Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA; in the Division of Gastroenterology and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts; and in the Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

Antibiotics are often crucial therapies, but their use comes at the expense of a person’s gut microbial community. Writing in Nature, Dai et al.1 report that diet can influence the severity of such microbial disturbance.

doi: https://doi.org/10.1038/d41586-026-02782-0

References

  1. Dai, A. et al. Nature https://doi.org/10.1038/s41586-026-11077-3 (2026).

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  2. Peled, J. U. et al. N. Engl. J. Med. 382, 822–834 (2020).

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  3. Stein-Thoeringer, C. K. et al. Science 366, 1143–1149 (2019).

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  4. Tanes, C. et al. Cell Host Microbe 29, 394–407 (2021).

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  5. Ng, K. M. et al. Cell Host Microbe 26, 650–665 (2019).

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Competing Interests

The authors declare no competing interests.

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